Table 5: ANOVA results: effect of the variables on , AUC, % entrapment (EE), swelling percentage (SR), shape factor (SF), and particle size (DM).

Factors AUC EE -ratio -ratio -ratio A 89.52 <0.001 16.48 144.1 <0.001 −1892 11.2 0.004 5.57 B 2072 <0.001 97.11 1070 <0.001 −6316 0.27 0.607 1.07 C 132.5 <0.001 24.56 136 <0.001 −2252 1.41 0.25 2.42 D 564 <0.001 50.67 251.7 <0.001 −3063 0.003 0.955 −0.12 E 172.9 <0.001 −28.06 52.87 <0.001 1404 1.27 0.274 2.30 F 83.07 <0.001 −19.44 21.36 <0.001 892.2 2.18 0.157 3.01 G 0.01 0.918 −0.22 0.01 0.921 −19.4 0.67 0.425 1.66 H 213.4 <0.001 −31.17 3.20 0.082 345.2 0.53 0.474 −1.49 Factors SR SF DM -ratio F-ratio -ratio A 1842 <0.001 592 34.79 <0.001 −0.072 12.78 <0.001 0.255 B 1208 <0.001 −587.2 0.78 0.383 0.013 2.19 0.148 0.128 C 808.8 <0.001 −480.5 11.9 <0.001 0.051 2.19 0.148 0.130 D 274.4 <0.001 279.9 69.35 <0.001 −0.124 1.69 0.201 0.115 E 0.00 0.99 −0.22 4.49 0.041 −0.032 2.73 0.108 −0.142 F 62.8 <0.001 −133.9 100.4 <0.001 −0.149 0.80 0.377 0.077 G 5856 <0.001 −1293 23.4 <0.001 −0.072 8.78 0.005 0.261 H 25.09 <0.001 84.64 15.63 <0.001 0.059 8.15 0.007 −0.251