Robust Optimization of Alginate-Carbopol 940 Bead Formulations

Table 6

Optimization process carried out in each variable for robust method.

Variable	Aim in Taguchi	Robust
𝑡50%	Smaller is best (to120 minutes)	𝐴1𝐵−1𝐶1𝐷0𝐸1𝐹−1𝐺−1𝐻1
AUC	Bigger is best	𝐴−1𝐵−1𝐶0𝐷0𝐸1𝐹0𝐺0𝐻1
EE	Bigger is best	𝐴1𝐵0𝐶0𝐷0𝐸1𝐹0𝐺1𝐻−1
SR	Bigger is best	𝐴1𝐵−1𝐶−1𝐷0𝐸0𝐹0𝐺−1𝐻1
SF	Bigger is best	𝐴−1𝐵0𝐶1𝐷−1𝐸0𝐹−1𝐺−1𝐻0
Dm	Smaller is best	𝐴−1𝐵−1𝐶0𝐷−1𝐸0𝐹−1𝐺−1𝐻1