Research Article
Upper Respiratory Tract Colonization by Gram-Negative Rods in Patients with Chronic Lymphocytic Leukemia: Analysis of Risk Factors
Table 1
Selected demographic, clinical, and laboratory parameters of the CLL patients.
| | Parameter | No. of patients (%) | Mean ± SD | Range |
| | Age | | | 43–80 | | Gender: | | | | | Males | 12 (40) | | | | Females | 18 (60) | | | | The Rai stage: | | | | | 0 | 8 (26.7) | | | | 1 | 8 (26.7) | | | | 2 | 11 (36.7) | | | | 3 | 3 (10.0) | | | | Period from diagnosis (years) | | | 0–11 | | No. of infections per year | | | 1–11 | | Type of infection: | | | | | URTIs | 12 (40.0) | | | | LRTIs | 5 (16.7) | | | | URTs+LRTIs | 6 (20.0) | | | | LTRIs+skin infections | 1 (3.3) | | | | URTIs+LRTIs+skin infections | 2 (6.7) | | | | Lymphocytes (%) | | | 48.3–89.3 | | Lymphocytes (103/mm3) | | | 5.3–90.9 | | Neutrophils (%) | | | 3.5–91.0 | | Neutrophils (103/mm3) | | | 1.2–20.5 | | IgA (mg/dL) | | | 3–380 | | IgG (mg/dL) | | | 320–1616 | | IgM (mg/dL) | | | 4–220 | | CD3+ cells (%) | | | 1.2–56.2 | | CD19+ cells (%) | | | 35.2–96.8 | | CD5+CD19+ cells (%) | | | 45–96.7 | | CD19+ZAP70+ cells (%) | | | 1.7–45.3 | | Negative | 21 (75.0) | | | | Positive | 7 (25.0) | | | | CD19+CD38+ cells (%) | | | 0.3–56.7 | | Negative | 20 (71.4) | | | | Positive | 8 (28.6) | | | | ZAP70 expression in relation to CD38 expression on B lymphocytes | | | | | ZAP70 (−), CD38 (−) | 18 (64.3) | | | | ZAP70 (+), CD38 (+) | 5 (17.9) | | | | ZAP70 (+), CD38 (−) | 2 (7.1) | | | | ZAP70 (−), CD38 (+) | 3 (10.7) | | | | CD19+CD25+ cells (%) | | | 1.9–89.8 | | Negative | 7 (25.0) | | | | Positive | 21(75.0) | | | | CD19+CD69+ cells (%) | | | 0.4–60.8 | | CD3+CD25+ cells (%) | | | 2.4–52.8 | | CD3+CD69+ cells (%) | | | 0.5–29.3 | | CD3+CD4+ cells (%) | | | 0.8–33.1 | | CD3+CD8+ cells (%) | | | 0.5–24.2 | | CD4+ to CD8+ cells ratio | | | 0.3–3.2 | | CD4+CD8+ cells (%) | | | 0.03–3.6 |
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URTIs: upper respiratory tract infections, LRTIs: lower respiratory tract infections.
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