Angiogenic Response to Major Lung Resection for Non-Small Cell Lung Cancer with Video-Assisted Thoracic Surgical and Open Access

Table 2

VEGF, Ang-1, Ang-2, sVEGFR1 and sVEGFR2 levels after VATS and open lung surgery.

	Preop^a	Day 1^a	𝑃	Day 3^a	𝑃
VEGF (pg/mL)
VATS	179.2 (100)	174.1 (88)	0.76	170.4 (93)	0.66
Open	246.9 (286)	391.9 (595)	0.72	486.1 (641)	0.17
𝑃	NS	NS		0.04
Ang-1 (pg/mL)
VATS	7504.3 (5944)	3423.3 (2783)	<0.0001	3623.9 (2963)	<0.0001
Open	7370.7 (6188)	6369.1 (7707)	0.28	7576.6 (8801)	0.47
𝑃	NS	NS		NS
Ang-2 (pg/mL)
VATS	1932.3 (718)	2581.2 (953)	0.001	2484 (1119)	0.01
Open	2502 (1236)	3384.2 (1501)	0.07	3378.9 (1287)	0.026
𝑃	0.052	0.05		0.026
sVEGFR1 (pg/mL)
VATS	100.1 (22)	140.6 (38)	<0.0001	116.7 (45)	0.042
Open	85.1 (45)	142.3 (59)	0.006	108.4 (52)	0.015
𝑃	NS	NS		NS
sVEGFR2 (pg/mL)
VATS	10469.1 (2220)	9244.2 (2299)	0.005	8524.4 (1680)	<0.0001
Open	11882 (3016)	9419.4 (2301)	<0.0001	8906.3 (2428)	<0.0001
𝑃	NS	NS		NS

^aMean (SD).