Research Article

MATN3 Gene Polymorphism Is Associated with Osteoarthritis in Chinese Han Population: A Community-Based Case-Control Study

Table 3

Genotype and allele frequencies and odds ratios of MATN3 SNP6 (rs8176070) in control, knee OA cases.

NormalAll knee OA 𝑃 aOR (95% CI)

Genotype 𝑛 = 3 1 2 (%) 𝑛 = 1 0 8 (%)
 bb37 (11.9)19 (17.6)
 Bb126 (40.4)49 (45.4)0.0611.662 (0.976–2.830)
 BB149 (47.8)40 (37.3)0.0212.402 (1.141–5.060)
Allele 𝑛 = 6 2 4 (%) 𝑛 = 2 1 6 (%)
 b424 (67.9)129 (59.7)
 B200 (32.1)87 (40.3)0.0003.143 (2.283–4.328)

𝑛 : number of samples.
a 𝑃 < 0 . 0 5 , significantly different, compared with the control group.