Research Article

Low-Dose Fluvastatin Prevents the Functional Alterations of Endothelium Induced by Short-Term Cholesterol Feeding in Rabbit Carotid Artery

Table 1

Body weights and plasma total cholesterol levels from all groups of rabbits.

Control groupCholesterol groupCholesterol + fluvastatin group

Body weight (kg)Start2.64 ± 0.082.69 ± 0.132.67 ± 0.07
End2.77 ± 0.092.56 ± 0.092.50 ± 0.07
Plasma total cholesterol (mmol/L)Start0.94 ± 0.151.30 ± 0.181.02 ± 0.18
End1.20 ± 0.1313.82 ± 1.88+9.40 ± 1.07*

+ 𝑃 < 0 . 0 0 1 , control versus cholesterol and * 𝑃 < 0 . 0 1 control versus cholesterol + fluvastatin, ANOVA followed by Bonferroni post hoc test. Data are expressed as means of five independent measurements using five animals in each group. Data are given ± S.E.M.