The Scientific World Journal

Research Article

Synthesis and Neuropharmacological Evaluation of Some Novel Quinoxaline 2, 3-Dione Derivatives

Table 2

Grip strength test.
GroupsTime taken to catch the wire with hind limbTotal time the animal catches the wireFalling timeFecal pellets
Control 8 . 5 6 7 ± 0 . 0 3 3 3 1 8 6 . 7 ± 0 . 0 2 8 9 2 . 6 ± 0 . 8 8 1 1 ± 0
Ethidium
Bromide 4 . 3 ± 0 . 1 0 0 1 4 3 . 0 ± 0 . 6 0 3 *** 1 2 4 . 7 ± 0 . 4 8 0 *** 4 . 3 ± 0 . 3 3 3 ***
Antioxidant 3 . 7 4 0 ± 0 . 0 7 4 8 *** 1 5 4 ± 1 . 1 4 0 *** 1 0 4 . 8 ± 0 . 9 8 5 *** 3 ± 0 . 3 1 6 2 **
Comp2a 3 . 3 2 0 ± 0 . 2 3 5 4 ** 1 5 1 . 2 ± 0 . 2 7 4 ** 9 9 . 2 0 ± 0 . 0 2 0 * 2 . 6 ± 0 . 2 4 4 9 *
Comp2b 3 . 2 ± 0 . 0 5 4 7 7 *** 1 4 8 . 4 ± 0 . 7 0 7 *** 1 0 5 ± 0 . 7 0 7 * 4 . 7 5 0 ± 0 . 4 7 8 **
Comp2c 1 . 6 8 ± 0 . 1 0 6 8 ** 1 6 1 . 4 ± 0 . 5 3 4 * 1 0 1 . 8 ± 0 . 9 1 6 ** 3 . 4 ± 0 . 4 ***
𝑃 < 0 . 0 5 ; ***extremely significant; **moderately significant; *significant.