Acute Effects of Vardenafil on Pulmonary Artery Responsiveness in Pulmonary Hypertension

Figure 2

Concentration- response curves (10⁻¹⁰–10⁻⁵ M; 𝑛=15) to vardenafil in control and pulmonary hypertensive rat pulmonary artery rings contracted by phenylephrine (10⁻⁶ M). Experimental values were calculated relative to the maximal changes from the contraction produced by phenylephrine in each tissue, which was taken as 100%. *𝑃<0.05 as compared with control.