A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim

Figure 2

(a) Visible absorption spectra of TMP (4.0×10⁻⁵M) at various concentrations of SDS at 298 K: (1) no SDS, (2) 2 mM, (3) 4 mM, (4) 8 mM, (5) 10 mM, (6) 20 mM SDS. (b) The absorbance change of 4.0×10⁻⁵ M TMP (below and above the CMC) with the concentration of SDS.

(a)

(b)