A Study on Solubilization of Poorly Soluble Drugs by Cyclodextrins and Micelles: Complexation and Binding Characteristics of Sulfamethoxazole and Trimethoprim

Table 2

Estimated surface excess (Γ_max) and molecular occupied area (A_min) for SDS and TX100 in the absence and presence of 4.0×10⁻⁵ M SMX and TMP at 298 K.

	SMX		TMP
	Γmax (mmol/m^2)	Amin × 10^−2(Å^2)	Γmax (mmol/m^2)	Amin × 10^−2 (Å^2)
SDS	5.23	3.17	2.99	5.55
TX100	2.55	6.51	3.02	5.50
		No drugs
	Γmax (mmol/m^2)		Amin × 10^−2(Å^2)
SDS	3.66		4.54
TX100	2.47		6.70