Regulating Drug Release Behavior and Kinetics from Matrix Tablets Based on Fine Particle-Sized Ethyl Cellulose Ether Derivatives: An In Vitro and In Vivo Evaluation

Table 4

Stability parameters of ciprofloxacin HCl CR tablets prepared at D : P ratio 10 : 3 (Mean ± SEM, 𝑛=6).

Periods of sampling	Hardness (kg)	Friability (%)	Appearance (colour)	Drug content (%)	Weight variation (%)
Before storage (0 time)	7.4±0.3	0.27±0.11	White	103±2	4±0.3
After 1 month	7.2±0.4	0.19±0.13	White	102±2	5±0.2
After 2 month	7.3±0.2	0.27±0.13	White	103±3	5±0.4
After 4 month	7.1±0.4	0.22±0.11	White	101±2	5±0.3
After 6 month	7.4±0.2	0.24±0.12	White	102±3	4±0.2