Review Article

Ferrous versus Ferric Oral Iron Formulations for the Treatment of Iron Deficiency: A Clinical Overview

Table 1

Differences between bivalent and trivalent oral iron preparations.

Iron supplementComments

Bivalent
 Ferrous fumarate (Fe2+) More adverse effects if not in a prolonged-release formulation
 Ferrous gluconate (Fe2+)
 Ferrous sulphate (Fe2+)
 Ferrous glycine sulphate (Fe2+)

TrivalentPoorer absorption
 Iron protein succinylate (Fe3+)More expensive
 Iron polymaltose complex (Fe3+)A greater number of intakes