Research Article

Preparation and In Vitro Evaluation of Tacrolimus-Loaded Ethosomes

Table 1

Physicochemical characteristics of tacrolimus-loaded liposomes and ethosomes.

LiposomesEthosomes

Particle size (nm)146 ± 1285 ± 13*
Polydispersity index 0 . 2 6 8 ± 0 . 0 5 1 0 . 2 9 8 ± 0 . 0 2 4
Entrapment efficiency (%) 6 5 . 3 ± 2 . 2 7 8 . 7 ± 3 . 3 **

* 𝑃 < 0 . 0 5 ; ** 𝑃 < 0 . 0 1 versus liposomes.