Outcome of R-CHOP or CHOP Regimen for Germinal Center and Nongerminal Center Subtypes of Diffuse Large B-Cell Lymphoma of Chinese Patients

Table 3

Cox proportional hazard regression analysis for CHOP and R-CHOP groups.

	CHOP				R-CHOP
	RR	95% CI		P	RR	95% CI		P
		Lower	Upper			Lower	Upper
OS
GCB versus non-GCB	2.125	1.196	3.776	0.010	1.712	0.757	3.872	0.197
Sex (male versus female)	2.057	1.192	3.550	0.010	0.550	0.240	1.260	0.158
Age (young versus elder)	3.350	1.911	5.871	0.000	1.972	0.853	4.562	0.112
Stage (early versus advance)	1.932	1.066	3.502	0.030	0.559	0.173	2.068	0.418
PFS
IPI (0-1 versus 2–5)	1.156	0.438	3.051	0.770	2.408	1.187	4.883	0.015
GCB versus non-GCB	2.463	1.385	4.382	0.003	1.664	0.739	3.747	0.219
Sex (male versus female)	1.869	1.102	3.170	0.020	0.562	0.247	1.276	0.168
Age (young versus elder)	3.464	1.994	6.017	0.000	2.473	1.223	5.002	0.012

RR indicates relative risk; CI: confidence interval; OS: overall survival; PFS: disease-free survival.