Clinical Study

The Association between Single-Nucleotide Polymorphisms of ORAI1 Gene and Breast Cancer in a Taiwanese Population

Table 1

Genotyping and allele frequency of ORAI1  gene in patients with breast cancer with or without recurrence.

Present (%)Absent (%)Present (%)Absent (%)DominantRecessiveAllelic
Genotype( 𝑛 = 2 6 )( 𝑛 = 3 5 2 )Allele( 𝑛 = 2 6 )( 𝑛 = 3 5 2 )P valueP valueP value

rs12320939TT2 (8.7)73 (21.1)T20 (43.5)321 (46.4)0.49540.15240.7016
TG16 (69.6)175 (50.6)G 26 (56.5)371 (53.6)
GG5 (21.7)98 (28.3)
rs12313273CC0 (0.0)22 (6.4)C10 (20.0)182 (26.4)0.53670.19290.3206
CT10 (40.0)138 (40.0)T40 (80.0)508 (73.6)
TT15 (60.0)185 (53.6)
rs7135617TT1 (4.5)57 (16.9)T15 (34.1)291 (43.2)0.56850.12670.2378
TG13 (59.1)177 (52.5)G29 (65.9)383 (56.8)
GG8 (36.4)103 (30.6)
rs6486795CC1 (4.5)40 (11.6)C15 (34.1)248 (36.2)0.78030.30550.7825
CT13 (59.1)168 (49.0)T29 (65.9)438 (63.8)
TT8 (36.4)135 (39.4)
rs712853CC5 (20.8)31 (8.9)C21 (43.8)220 (31.8)0.25110.05770.0873
CT11 (45.8)158 (45.7)T27 (56.2)472 (68.2)
TT8 (33.4)157 (45.4)