Table 2: Structure activity and values calculated.

Compounds Structures Anti-inflammatory activity
(dose 250 mg·Kg−1)

3a ( )1.53 ± 0.7233.7
3b ( )925925.tab.002a1.74 ± 0.7169.0
3c ( ) 2.04 ± 0.7144.0

5a ( )2.37 ± 0.6017.0
5b ( )925925.tab.002b2.59 ± 0.6025.0
5c ( )2.89 ± 0.5956.2

ASA925925.tab.002c1.19 ± 0.2373.0

Ibuprofen925925.tab.002d3.72 ± 0.2368.0

values were calculated using Advanced Chemistry Development (ACD/Labs Algorithm Version: v5.0.0.184).