Evolution of the C-Type Lectin-Like Receptor Genes of the DECTIN-1 Cluster in the NK Gene Complex
Figure 3
Organization and transcriptional orientation of the genes in the human, mouse and opossum DECTIN-1 cluster. (a) Physical map comparing the DECTIN-1 cluster in the centromeric part of the human NK complex with the corresponding region of the mouse and opossum NK complex, extending from the myeloid inhibitory C-type lectin-like receptor (MICL) gene to the CD94 gene. Linkage and orientation of the genes in the myeloid cluster of the NK gene complex are depicted. (b) Possible course of events leading from the non-primate to the primate mammalian configuration of the myeloid cluster between the genes encoding MICL and CLEC-1. Modified and reprinted with permission of John Wiley & Sons, Inc. 2010 from [21].
