Clinical Study

Expression and Clinical Significance of Antiapoptotic Gene (Survivin) in NB4 and Acute Promyelocytic Leukemia Cells

Table 1

The results of survivin mRNA expression in de novo, relapse, and remission APL.

Group 𝑁 survivin-mRNA expression
positive 𝑃 value

(1) de novo and relapse*36 24 (67%)
L type (+)#2819 (68%)
S type (+)85 (63%)
(2) remission&228 (36%)
(3) acute leukemia2321 (91%)

Compared by remission 𝑥 2 = 5 . 0 7 , 𝑃 = 0 . 0 2 4 ; # 𝑥 2 = 4 . 9 2 , 𝑃 = 0 . 0 2 7 ; compared by acute leukemia 𝑥 2 = 4 . 7 1 , 𝑃 = 0 . 0 3 ; & 𝑥 2 = 1 4 . 8 1 , 𝑃 = 0 . 0 0 .