Supercooling Agent Icilin Blocks a Warmth-Sensing Ion Channel TRPV3
Figure 2
(a) Representative recordings showing an inhibition of mTRPV3 activity at different holding potentials. The upper and lower part of the trace shows a block of 2-APB-induced mTRPV3 activity at + or −40 mV holding potentials, respectively. (b) Quantification of the data from six experiments as explained above. (c) The upper and lower part of the trace shows a block of camphor induced mTRPV3 activity at + or −40 mV holding potentials, respectively. (d) Quantification of the data from six experiments as explained above. All values are expressed as mean ± SEM.
