Fusion Pore Diameter Regulation by Cations Modulating Local Membrane Anisotropy
Figure 2
The application of a cAMP increasing agent increases the rhythmic openings and closures of an individual fusion pore, recorded in resting lactotrophs. Membrane capacitance recordings demonstrate the effects of a cAMP increasing agent (dbcAMP, 10 mM) (b) in comparison to the control experiment (a). The capacitance trace demonstrates changes between low and high states, corresponding to effectively closed and open fusion pore states.
