Alveolar Overdistension as a Cause of Lung Injury: Differences among Three Animal Species

Table 1

Histological score.

	Pig groups		Rat groups
	P-NtV	P-HtV	Rat-NtV	Rat-HtV
Oedema^a	1.44±0.86	1.88±0.62	0.00±0.00	0.00±0.00
Neutrophil infiltration^a	1.49±1.20	1.72±1.58	0.40±0.54	0.00±0.00
Haemorrhage	0.16±0.28	0.27±0.68	0.60±0.54	0.40±0.54
Epithelial desquamation	0.11±0.17	0.00±0.00	0.00±0.00	0.00±0.00
Hyaline membrane^b	0.05±0.13	0.85±0.69	0.00±0.00	0.00±0.00
Total score^a	3.48±2.37	4.41±1.96	1.00±1.00	0.40±0.54

Values are mean ± SD. P-NtV: pigs with normal tidal volume; P-HtV: pigs with high tidal volume; Rat-NtV: rats with normal tidal volume; Rat-HtV: rats with high tidal volume.
^a𝑃<0.05 between pig and rat groups.
^b𝑃<0.05 between P-HtV and P-NtV groups.