Research Article

Alveolar Overdistension as a Cause of Lung Injury: Differences among Three Animal Species

Table 2

Respiratory parameters and wet/dry weight ratio.

Pig groupsRat groups
P-NtVP-HtVRat-NtVRat-HtV

Tidal volume (mL)a, b 2 7 0 . 0 ± 3 1 . 6 1 5 8 3 . 3 ± 5 1 . 6 3 . 7 ± 0 . 3 1 5 . 8 ± 1 . 7
Plateau airway pressures (cm H2O)a, b 1 3 . 5 ± 1 . 7 5 7 . 3 ± 8 . 2 1 2 . 0 ± 1 . 1 3 8 . 3 ± 4 . 3
Wet/dry ratioa, b 4 . 3 3 ± 0 . 9 9 5 . 6 0 ± 0 . 3 7 4 . 4 3 ± 0 . 1 0 4 . 1 0 ± 0 . 0 7

Values are mean ± SD. P-NtV: pigs with normal tidal volume; P-HtV: pigs with high tidal volume; Rat-NtV: rats with normal tidal volume; Rat-HtV: rats with high tidal volume.
a 𝑃 < 0 . 0 1 between P-HtV and P-NtV groups.
b 𝑃 < 0 . 0 1 between Rat-HtV and Rat-NtV groups.