Research Article
Association of FAS and FAS Ligand Genes Polymorphism and Risk of Systemic Lupus Erythematosus
Table 4
Synergic effect of FAS A-670G and FAS ligand C-844T polymorphisms in SLE patients and controls.
| | FAS A-670G/FASL C-844T | SLE
| Control
| P value | OR (95% CI) |
| | GG/TT | 7 (6.6) | 13 (9.9) | | Ref = 1 | | AG/CT | 29 (27.4) | 37 (25.9) | 0.3 | 1.4 (0.5–4.2) | | AG/CC | 25 (23.6) | 30 (21) | 0.3 | 1.4 (0.5–4.6) | | AA/TT | 2 (1.9) | 8 (5.6) | 0.3 | 0.45 (0.08–2.9) | | AA/CT | 14 (13.2) | 18 (12.6) | 0.4 | 1.5 (0.5–5) | | AA/CC | 18 (17) | 9 (6.3) | 0.03 | 3.7 (1.1–12.5) | | GG/TT, GG/CT, AG/TT | 11 (10.4) | 30 (20) | | Ref = 1 | | AG/CT | 29 (27.4) | 37 (25.9) | 0.06 | 2.1 (0.9–5) | | AG/CC | 25 (23.6) | 30 (21) | 0.05 | 2.3 (0.9–5.4) | | AA/TT | 2 (1.9) | 8 (5.6) | 0.5 | 0.67 (0.13–3.3) | | AA/CT | 14 (13.2) | 18 (12.6) | 0.5 | 2.1 (0.8–5) | | AA/CC | 18 (17) | 9 (6.3) | 0.001 | 5.6 (1.9–15.6) |
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