Association, Haplotype, and Gene-Gene Interactions of the HPA Axis Genes with Suicidal Behaviour in Affective Disorders

Table 7

Multilocus interaction model for the risk of suicide attempts with the NR3C1. AVPR1b and CRHR1 genes by the MDR method.

Model	Loci combination	Testing balanced accuracy (%)	Cross-validation consistency (%)	𝑃 value
2-locus	Rs258813 of NR3C1 and rs110402 of CRHR1	47	30	0.989
3-locus	Rs41423247 and rs258813 of NR3C1 and rs110402 of CRHR1	52	50	0.760
4-locus	Rs41423247 and rs258813 of NR3C1. rs28373064 of AVPR1b and rs110402 of CRHR1	50	90	0.589