Research Article

TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research

Table 1

Morphometric measurements.

Measurements Meaning Units

Localization - coordinates Pixels
Area Vessel contour area Physical units ( m2)
Size Vessel width and height Physical units ( m)
Perimeter Perimeter Physical units ( m)
Angle Angle between the horizontal axis and the first side (i.e., length) Radians
Vascular density Physical units (vessel number/ m2)
Aspect
Roundness
Perimeter ratio
Deformity Convex area − area Physical units ( m)
Shape
Vertices Calculates the approximate contour polygon vessel with less distance between vertices using the Douglas-Peucker algorithm [19]

and .
are the Hu moments of the normal and convex contour area , respectively, and represents the seven Hu invariant moments.
*These axes correspond to the best-fitting ellipsoid of the vessel contour.