Table 2: Tyrosinase inhibitory activity of new molecules and kojic acid.

Analogs ( )Chemical structureIA 60 min (%)IA 120 min (%)IA50 (µg·mL−1)

A274643.table.002a87.83 ± 1.50a 85.60 ± 0.61h95.57 ± 0.74p
B274643.table.002b82.37 ± 1.18b81.50 ± 0.50i70.60 ± 1.22p,q
C274643.table.002c77.43 ± 0.59a,c74.57 ± 0.65h,j65.67 ± 0.60p,r
D274643.table.002d75.13 ± 0.84a,b,d74.00 ± 0.44h,l140.13 ± 0.75p,q,r,s
E274643.table.002e79.50 ± 0.70a,e68.83 ± 0.06h,i,m79.03 ± 1.78s,t
F274643.table.002f85.47 ± 0.76c,d,f84.40 ± 0.85j,l,m,n88.80 ± 0.44q,r,s,u
Resveratrol274643.table.002g69.47 ± 3.44a,b,c,e,f,g75.52 ± 4.99h,n,o87.10 ± 10.36r,s,v
Kojic acid
274643.table.002h84.00 ± 1.41d,g55.60 ± 0.56h,i,j,l,m,n,o5.30 ± 0.17p,q,r,s,t,u,v

*Means followed by the same letters differ by ANOVA followed by Tukey post hoc test (a–v ).