Protein Detection with Potentiometric Aptasensors: A Comparative Study between Polyaniline and Single-Walled Carbon Nanotubes Transducers

<table>Scheme depicting charge competition and TBA-thrombin binding. (a) When the thrombin is not in the system, TBA tends to remain attached to PANI backbone due to charge attraction. (b) TBA starts to dislocate from PANI surface through thrombin. (c) Positively charged active site of the thrombin binds to the TBA which leads to a potentiometric signal.</table>

The Scientific World Journal

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Scheme 1

Scheme 1: Protein Detection with Potentiometric Aptasensors: A Comparative Study between Polyaniline and Single-Walled Carbon Nanotubes Transducers 