Studies of the Interaction between Isoimperatorin and Human Serum Albumin by Multispectroscopic Method: Identification of Possible Binding Site of the Compound Using Esterase Activity of the Protein

Figure 11

Crystal structure of HSA and the positions of single tryptophan residue (Trp 214) and also the binding site of isoimperatorin in HSA. Protein backbone is shown in the “cartoon” representation, and isoimperatorinand Trp 214 residue in the site I are shown in the “stick” representation. The isoimperatorin and Trp 214 structures are represented by the red and blue colors. The crystal structure of protein was obtained from Protein Data Bank (1BM0). For interpretation of references to color in this figure legend, the reader is referred to the web version of this paper.