Von Willebrand Factor Antigen Predicts Response to Double Dose of Aspirin and Clopidogrel by PFA-100 in Patients Undergoing Primary Angioplasty for St Elevation Myocardial Infarction
Table 1
Clinical, hemodynamic, and laboratory data of patients recruited.
Group 0 (standard therapy) ()
Group 1 (tailored therapy) ()
value
Male sex (%)
41 (71)
38 (65)
0.51
Age*
0.33
BMI*
0.77
LVEF*
0.64
Current smoking, (%)
16 (28)
16 (28)
0.98
LDL-Cholesterol*
0.51
Diabetes mellitus, (%)
16 (28)
18 (31)
0.41
Hypertension, (%)
31 (54)
35 (61)
0.27
Time to balloon, min*
0.42
Pre-PCI Abciximab, (%)
6 (10)
5 (8)
0.59
Pre-PCI TIMI flow*
0.89
Post-PCI TIMI flow*
0.71
Number of diseased vessels*
0.86
Number of treated vessels*
0.78
Number of balloon/patient
0.43
Number of stents/patient*
0.65
Number of DES, (%)
29 (50)
27 (48)
0.63
Stent length/patient, mm*
0.73
Time between PCI and PFA-100, h*
0.86
Hemoglobin, g/dL*
0.84
Leukocytes, g/L*
0.67
Platelets, 103 g/L*
0.51
High sensitivity RCP, mg/dL
0.64
Fibrinogen, g/L*
0.18
Creatinine, mg/dL*
0.64
Cytochrome P450 metabolized drugs, (%)**
58 (100)
57 (98)
0.97
BMI: body mass index; CAD: coronary artery disease; TIMI: thrombolysis in myocardial infarction; DES: drug eluting stents; LVEF: left ventricular ejection fraction; PCI: percutaneous coronary intervention; PFA: platelet function analyzer. *Mean standard deviation; **calcium channels antagonists, high dose statins.
