The Effect of Reagents Mimicking Oxidative Stress on Fibrinogen Function

Figure 2

Representative curves of thrombin-catalyzed fibrin polymerization. Fibrin clot formation from modified (modification times: MDA 30 min, NaOCl 5 min, and SIN-1 30 min) or control fibrinogen (1 mg/mL) was monitored at 350 nm after the addition of thrombin (0.5 U/mL).