The Effect of Reagents Mimicking Oxidative Stress on Fibrinogen Function

Figure 4

Dynamic adhesions (relative surface coverage) in the presence of control and modified fibrinogen. Fibrinogen (Fbg) modified by (a) MDA, (b) NaOCl, and (c) SIN-1. Data are expressed as a percentage of surface coverage in the presence of modified fibrinogens relatively to surface coverage in the presence of control fibrinogen. Results are represented as mean±SD of nine values from three independent experiments (three values per experiment). Student’s 𝑡-test probability: *𝑃<0.05; **𝑃<0.01.

(a)

(b)

(c)