Polymorphisms but Not Mutations of the KCNQ1 Gene Are Associated with Lone Atrial Fibrillation in the Chinese Han Population

Table 3

Twelve known polymorphisms found in LAF patients.

SNPs	Regions	Minor allele	Amino acid change	Han Chinese MAF
rs1800170	Exon2	T	I145I	0.091
rs59233444	Intron2	GG	—	N.A
rs12786951	Intron6	G	—	0.489
rs12577654	Intron12	T	—	0.057
rs760419	Intron12	G	—	0.318
rs163160	Intron12	G	—	0.244
rs2075870	Intron12	A	—	0.170
rs1057128	Exon13	A	S546S	0.289
rs163150	Intron14	A	—	0.289
rs2519184	3′-UTR	A	—	0.034
rs45510192	3′-UTR	A	—	N.A
rs394656	3′-UTR	C	—	N.A

MAF (minor allele frequency) of Han Chinese is based on HapMap Data; N.A: not available from HapMap Data for Han Chinese population.