The Role of Clomipramine in Potentiating the Teratogenic Effects of Caffeine in Pregnant Rats: A Histopathological Study
Figure 2
Histopathological slides of the frontal section of the head, 17-day-fetuses in the control group (a) and the group that received a combination of clomipramine and caffeine in high doses (b) (H&E staining, 4x). In the control group (a), the nasal septum is attached to the roof of the mouth and nostrils (A) are completely separated from the oral cavity. Tongue (B) is shown to be perfectly in the mouth and located in its normal place. In the fetus from the group treated with clomipramine and caffeine in high doses (b), there is bilateral clefting of the palate (C) and tongue inside the mouth is flat (D).
