Review Article

Multiple Myeloma and Kidney Disease

Table 2

Associations between clinical manifestations and types of kidney injury in MM [10].

Predominant renal syndromeMajor types of renal lesions

Acute kidney injury (AKI)Myeloma cast nephropathy
Acute tubular necrosis
Iatrogenic effects
Direct infiltration of renal parenchyma
Acute tubulointerstitial nephropathy

Proteinuria/nephrotic syndromeMonoclonal Ig deposition disease (MIDD)
Amyloidosis
Rare types of glomerular involvement

Chronic kidney disease (CKD)Amyloidosis
Myeloma cast nephropathy
Monoclonal Ig deposition disease (MIDD)

Fanconi syndromeProximal tubulopathy