Review Article

Multiple Myeloma and Kidney Disease

Table 3

Staging of acute kidney injury [20].

StageSerum creatinineUrine output

11.5–1.9 times baseline
OR
≥0.3 mg/dL (≥26.5 mmol/L) increase
<0.5 mL/kg/h for
6–12 h

22.0–2.9 times baseline<0.5 mL/kg/h for
≥12 h

33.0 times baseline
OR
Increase in serum creatinine to
≥4.0 mg/dL (≥353.6 mmol/L)
OR
Initiation of renal replacement therapy
OR, in patients <18 years, decrease in
eGFR to <35 ml/min per 1.73 m2
<0.3 mL/kg/h for
≥24 h
OR
Anuria for ≥12 h