507872.fig.003a
(a)
507872.fig.003b
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507872.fig.003c
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507872.fig.003d
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507872.fig.003e
(e)
Figure 3: Action potential and calcium transient recordings from rabbit (left) and human (right) SA nodal myocytes and associated numerical reconstructions of membrane currents. (a) Recorded membrane potential . (b) Recorded intracellular calcium concentration ( ). (c) Time derivative of (d ). (d) Reconstructed hyperpolarization-activated inward current ( ). The noisy trace in gray is the net membrane current ( ) computed from , where denotes membrane capacitance. (e) Reconstructed sodium-calcium exchange current ( ), with the net membrane current in gray.