Research Article

Nexfin Noninvasive Continuous Hemodynamic Monitoring: Validation against Continuous Pulse Contour and Intermittent Transpulmonary Thermodilution Derived Cardiac Output in Critically Ill Patients

Table 2

Comparison of several neurological, respiratory, and hemodynamic variables and dose of the used drugs between the start and the end (at 8 hours) of the study period.

Number (%)Start8 hoursP-value

Neurological
 Propofol (mg/kg/hr)35 (71%) 0.99
 Midazolam (mg/kg/hr)31 (69%) 0.81
 Remifentanil ( g/kg/min)39 (87%) 0.80
 Cisatracurium (mg/kg/hr)9 (20%) 0.77
 SAS (1–7)45 (100%) 0.28
 GCS (3–15)45 (100%) 0.67
Respiratory system
 pO2/FIO245 (100%) 0.64
 Minute ventilation (L/min)45 (100%) 0.92
 pH45 (100%) 0.45
 EVLWI (mL/kg)45 (100%) 0.89
Hemodynamics
 Norepinephrine ( g/kg/min)35 (78%) 0.90
 Dobutamine ( g/kg/min)27 (60%) 0.49
 MAP (mmHg)45 (100%) 0.41
 Heart rate (BPM)45 (100%) 0.66
 CVP (mmHg)45 (100%) 0.65
 TDCO (L/min)45 (100%) 0.14
 GEF (%)45 (100%) 0.45
 GEDVI (mL/BSA)45 (100%) 0.56
 SVRI (dyne·s·cm−5/m²)45 (100%) 0.56
 SVV (%)45 (100%) 0.12
 PPV (%)45 (100%) 0.17
Other
 IAP (mmHg)45 (100%) 0.15
 Body Temperature (°C)45 (100%) 0.76

CVP: central venous pressure.
EVLWI: extravascular lung water index.
GCS: Glasgow coma scale.
GEDVI: global end-diastolic volume index.
GEF: global ejection fraction.
IAP: intra-abdominal pressure.
MAP: mean arterial pressure.
PPV: pulse pressure variation.
SAS: sedation and agitation scale.
SVRI: systemic vascular resistance index.
SVV: stroke volume variation.
TDCO: thermodilution cardiac output.