About this Journal Submit a Manuscript Table of Contents
The Scientific World Journal
Volume 2013 (2013), Article ID 543696, 6 pages
http://dx.doi.org/10.1155/2013/543696
Review Article

Goblet Cell Carcinoids of the Appendix

Department of Medicine V, Aarhus University Hospital, 44 Norrebrogade, 8000 Aarhus C, Denmark

Received 11 November 2012; Accepted 29 November 2012

Academic Editors: H. C. Lin, D. Morris, and L. Roncucci

Copyright © 2013 Nanna Holt and Henning Grønbæk. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. B. Abt and S. L. Carter, “Goblet cell carcinoid of the appendix. An ultrastructural and histochemical study,” Archives of Pathology and Laboratory Medicine, vol. 100, no. 6, pp. 301–306, 1976. View at Scopus
  2. N. H. Anderson, J. E. Somerville, C. F. Johnston, D. M. Hayes, K. D. Buchanan, and J. M. Sloan, “Appendiceal goblet cell carcinoids: a clinicopathological and immunohistochemical study,” Histopathology, vol. 18, no. 1, pp. 61–65, 1991. View at Scopus
  3. P. H. Cooper and R. L. Warkel, “Ultrastructure of the goblet cell type of adenocarcinoid of the appendix,” Cancer, vol. 42, no. 6, pp. 2687–2695, 1978. View at Scopus
  4. R. Kanthan, A. Saxena, and S. C. Kanthan, “Goblet cell carcinoids of the appendix: immunophenotype and ultrastructural study,” Archives of Pathology and Laboratory Medicine, vol. 125, no. 3, pp. 386–390, 2001. View at Scopus
  5. B. T. Lin and A. M. Gown, “Mixed carcinoid and adenocarcinoma of the appendix: report of 4 cases with immunohistochemical studies and a review of the literature,” Applied Immunohistochemistry & Molecular Morphology, vol. 12, no. 3, pp. 271–276, 2004. View at Scopus
  6. D. M. Ramnani, I. I. Wistuba, C. Behrens, A. F. Gazdar, L. H. Sobin, and J. Albores-Saavedra, “K-ras and p53 mutations in the pathogenesis of classical and goblet cell carcinoids of the appendix,” Cancer, vol. 86, no. 1, pp. 14–21, 1999.
  7. M. Stancu, T. T. Wu, C. Wallace, P. S. Houlihan, S. R. Hamilton, and A. Rashid, “Genetic alterations in goblet cell carcinoids of the vermiform appendix and comparison with gastrointestinal carcinoid tumors,” Modern Pathology, vol. 16, no. 12, pp. 1189–1198, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. S. G. Subbuswamy, N. M. Gibbs, C. F. Ross, and B. C. Morson, “Goblet cell carcinoid of the appendix,” Cancer, vol. 34, no. 2, pp. 338–344, 1974. View at Scopus
  9. F. Gagné, P. Fortin, V. Dufour, and C. Delage, “Tumors of the appendix associating histologic features of carcinoid and adenocarcinoma,” Annales d'Anatomie Pathologique, vol. 14, no. 4, pp. 393–406, 1969. View at Scopus
  10. X. Gui, L. Qin, Z. H. Gao, V. Falck, and N. Harpaz, “Goblet cell carcinoids at extraappendiceal locations of gastrointestinal tract: an underrecognized diagnostic pitfall,” Journal of Surgical Oncology, vol. 103, no. 8, pp. 790–795, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. P. H. Watson and A. Alguacil-Garcia, “Mixed crypt cell carcinoma. A clinicopathological study of the so-called ‘Goblet cell carcinoid’,” Virchows Archiv A, vol. 412, no. 2, pp. 175–182, 1987. View at Scopus
  12. L. H. Tang, J. Shia, R. A. Soslow et al., “Pathologic classification and clinical behavior of the spectrum of goblet cell carcinoid tumors of the appendix,” American Journal of Surgical Pathology, vol. 32, no. 10, pp. 1429–1443, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. Y. Jiang, H. Long, T. Li, W. Wang, H. Liu, and X. Zhang, “Schistosomiasis may contribute to goblet cell carcinoid of the appendix,” Journal of Parasitology, vol. 98, no. 3, pp. 565–568, 2012. View at Publisher · View at Google Scholar
  14. A. C. Goede, M. E. Caplin, and M. C. Winslet, “Carcinoid tumour of the appendix,” British Journal of Surgery, vol. 90, no. 11, pp. 1317–1322, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. K. Hemminki and X. Li, “Incidence trends and risk factors of carcinoid tumors: a nationwide epidemiologic study from Sweden,” Cancer, vol. 92, no. 8, pp. 2204–2210, 2001.
  16. M. E. McCusker, T. R. Coté, L. X. Clegg, and L. H. Sobin, “Primary malignant neoplasms of the appendix: a population-based study from the surveillance, epidemiology and end-results program, 1973–1998,” Cancer, vol. 94, no. 12, pp. 3307–3312, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. T. H. Pham, B. Wolff, S. C. Abraham, and E. Drelichman, “Surgical and chemotherapy treatment outcomes of goblet cell carcinoid: a tertiary cancer center experience,” Annals of Surgical Oncology, vol. 13, no. 3, pp. 370–376, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. B. Varisco, B. McAlvin, J. Dias, and D. Franga, “Adenocarcinoid of the appendix: is right hemicolectomy necessary? A meta-analysis of retrospective chart reviews,” American Surgeon, vol. 70, no. 7, pp. 593–599, 2004. View at Scopus
  19. P. Bucher, P. Gervaz, F. Ris, W. Oulhaci, J. F. Egger, and P. Morel, “Surgical treatment of appendiceal adenocarcinoid (goblet cell carcinoid),” World Journal of Surgery, vol. 29, no. 11, pp. 1436–1439, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. S. J. Connor, G. B. Hanna, and F. A. Frizelle, “Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies,” Diseases of the Colon & Rectum, vol. 41, no. 1, pp. 75–80, 1998. View at Publisher · View at Google Scholar · View at Scopus
  21. U. Knigge and C. P. Hansen, “Appendicial carcinoid tumors and goblet cell carcinoids,” Ugeskrift for Læger, vol. 172, no. 22, pp. 1678–1681, 2010. View at Scopus
  22. E. Liu, D. A. Telem, R. R. Warner, A. Dikman, and C. M. Divino, “The role of Ki-67 in predicting biological behavior of goblet cell carcinoid tumor in appendix,” The American Journal of Surgery, vol. 202, no. 4, pp. 400–403, 2011. View at Publisher · View at Google Scholar
  23. Y. Jiang, H. Long, W. Wang, H. Liu, Y. Tang, and X. Zhang, “Clinicopathological features and immunoexpression profiles of goblet cell carcinoid and typical carcinoid of the appendix,” Pathology and Oncology Research, vol. 17, no. 1, pp. 127–132, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. C. Toumpanakis, R. A. Standish, E. Baishnab, M. C. Winslet, and M. E. Caplin, “Goblet cell carcinoid tumors (adenocarcinoid) of the appendix,” Diseases of the Colon & Rectum, vol. 50, no. 3, pp. 315–322, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. K. O. Alsaad, S. Serra, A. Schmitt, A. Perren, and R. Chetty, “Cytokeratins 7 and 20 immunoexpression profile in goblet cell and classical carcinoids of appendix,” Endocrine Pathology, vol. 18, no. 1, pp. 16–22, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. J. A. Butler, A. Houshiar, F. Lin, S. E. Wilson, N. P. Lang, and S. A. Curley, “Goblet cell carcinoid of the appendix,” The American Journal of Surgery, vol. 168, no. 6, pp. 685–687, 1994. View at Publisher · View at Google Scholar · View at Scopus
  27. R. L. Warkel, P. H. Cooper, and E. B. Helwig, “Adenocarcinoid, a mucin-producing carcinoid tumor of the appendix: a study of 39 cases,” Cancer, vol. 42, no. 6, pp. 2781–2793, 1978. View at Scopus
  28. K. T. Chen, “Appendiceal adenocarcinoid with ovarian metastasis,” Gynecologic Oncology, vol. 38, no. 2, pp. 286–288, 1990. View at Publisher · View at Google Scholar · View at Scopus
  29. H. Mahteme and P. H. Sugarbaker, “Treatment of peritoneal carcinomatosis from adenocarcinoid of appendiceal origin,” British Journal of Surgery, vol. 91, no. 9, pp. 1168–1173, 2004. View at Publisher · View at Google Scholar · View at Scopus
  30. U. Plöckinger, A. Couvelard, M. Falconi et al., “Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated tumour/carcinoma of the appendix and goblet cell carcinoma,” Neuroendocrinology, vol. 87, no. 1, pp. 20–30, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. R. R. P. Warner and T. M. O'Dorisio, “Radiolabeled peptides in diagnosis and tumor imaging: clinical overview,” Seminars in Nuclear Medicine, vol. 32, no. 2, pp. 79–83, 2002. View at Scopus
  32. B. Eriksson, M. Bergstrom, A. Sundin, C. Juhlin, H. Orlefors, K. Oberg, et al., “The role of PET in localization of neuroendocrine and adrenocortical tumors,” Annals of the New York Academy of Sciences, vol. 970, pp. 159–169, 2002. View at Publisher · View at Google Scholar
  33. U. F. Pape, A. Perren, B. Niederle, D. Gross, T. Gress, F. Costa, et al., “ENETS consensus guidelines for the management of patients with neuroendocrine neoplasms from the jejuno-ileum and the appendix including goblet cell carcinomas,” Neuroendocrinology, vol. 95, no. 2, pp. 135–156, 2012. View at Publisher · View at Google Scholar
  34. R. C. Thirlby, C. S. Kasper, and R. C. Jones, “Metastatic carcinoid tumor of the appendix. Report of a case and review of the literature,” Diseases of the Colon & Rectum, vol. 27, no. 1, pp. 42–46, 1984. View at Scopus
  35. J. C. Byrn, J. L. Wang, C. M. Divino, S. Q. Nguyen, and R. R. P. Warner, “Management of goblet cell carcinoid,” Journal of Surgical Oncology, vol. 94, no. 5, pp. 396–402, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. J. P. Boudreaux, D. S. Klimstra, M. M. Hassan et al., “The NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the jejunum, ileum, appendix, and cecum,” Pancreas, vol. 39, no. 6, pp. 753–766, 2010. View at Publisher · View at Google Scholar · View at Scopus
  37. P. S. Pahlavan and R. Kanthan, “Goblet cell carcinoid of the appendix,” World Journal of Surgical Oncology, vol. 3, article 36, 2005. View at Publisher · View at Google Scholar · View at Scopus
  38. P. Cashin, P. Nygren, P. Hellman, D. Granberg, H. Andréasson, and H. Mahteme, “Appendiceal adenocarcinoids with peritoneal carcinomatosis treated with cytoreductive surgery and intraperitoneal chemotherapy: a retrospective study of in vitro drug sensitivity and survival,” Clinical Colorectal Cancer, vol. 10, no. 2, pp. 108–112, 2011. View at Publisher · View at Google Scholar · View at Scopus