Application of HPLC with ELSD Detection for the Assessment of Azelaic Acid Impurities in Liposomal Formulation
Figure 4
Chromatograms of HPLC-ELSD assessments: L—placebo, liposomal form of azelaic acid without the active substance; LA—liposomal form of azelaic acid; P1 and P2—impurities originating from the components of the formulation; AA—azelaic acid; I4 and I5—identified impurities; and U1–U5—unidentified impurities observed in the liposomal formulation of the azelaic acid.
