Genetic Markers Associated to Dyslipidemia in HIV-Infected Individuals on HAART

Table 1

Genotypic and allelic frequencies of polymorphisms analyzed.

Polymorphisms	Genotypic frequency	Allelic frequency
APOA5 −1131T>C (rs662799)^a		T	C
T/T	515 (84.7)	0.92	0.08
T/C	90 (14.8)
C/C	3 (0.5)
Total	608
APOA5 S19W (56C>G; rs3135506)^a		C	G
C/C	500 (82)	0.90	0.10
C/G	103 (16.9)
G/G	7 (1.1)
Total	610
APOB SP Ins/Del (rs17240441)^a		Ins	Del
Ins/ins	193 (47.3)	0.70	0.30
Ins/del	176 (43.1)
Del/del	39 (9.6)
Total	408
APOB XbaI, 7673C>T (rs693)^a		C	T
C/C	122 (30)	0.55	0.45
C/T	203 (49.9)
T/T	82 (20.1)
Total	407
APOC3 3238C>G (rs5128)^b		C	G
C/C	478 (78.8)	0.89	0.11
C/G	127 (20.9)
G/G	2 (0.3)
Total	607
APOE ^a		E2	E3	E4
E2/E2	5 (0.8)	0.07	0.79	0.14
E2/E3	67 (11.2)
E2/E4	9 (1.5)
E3/E3	379 (63.6)
E3/E4	120 (20.1)
E4/E4	16 (2.7)
Total	596
LDLR intron 19G>T (rs6511720)^a		G	T
G/G	487 (80.2)	0.90	0.10
G/T	113 (18.6)
T/T	7 (1.2)
Total	607
SCAP 2386A>G (rs12487736)^a		A	G
A/A	168 (27.7)	0.52	0.48
A/G	296 (48.9)
G/G	142 (23.4)
Total	606

The difference in the number of individuals among single nucleotide polymorphisms (SNPs) is due to failure in genotyping some SNPs in the whole sample.
Genotypic frequencies presented as number of patients (%).
^a𝜒² test for Hardy-Weinberg equilibrium; 𝑃>0.05.
^b𝜒² test for Hardy-Weinberg equilibrium; 𝑃=0.032.