Comparison of Long-Term Effect of Dual-Chamber Pacing and Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy
Table 1
Parameter
ASA ()
DDD pacing ()
value**
Mean (SD)
Median (95% CI)
value*
Mean (SD)
Median (95% CI)
value*
Age (years)
54.4 (13.69)
54.0 (50.0; 60.0)
50.0 (16.18)
49.0 (43.0; 58.0)
0.180
Follow up (months)
86.9 (23.14)
80.0 (74.0; 90.0)
101.2 (48.78)
109.5 (88.0; 132.0)
0.069
NYHA class
Baseline
2.80 (0.478)
3.00 (3.0; 3.0)
2.65 (0.541)
3.00 (2.0; 3.0)
0.350
Final
1.66 (0.778)
1.25 (1.0; 2.0)
2.13 (0.576)
2.00 (2.0; 2.5)
0.005
Difference (final-baseline)
−1.13 (0.742)
−1.00 (−1.5; −1.0)
<0.001
−0.52 (0.561)
−0.50 (−1.0; 0.0)
<0.001
0.001
LVOTG (mmHg)
Baseline
73.0 (37.82)
70.0 (54.0; 80.0)
81.7 (43.63)
78.5 (55.0; 100.0)
0.322
Final
23.6 (26.42)
10.0 (7.0; 25.0)
20.8 (21.19)
11.0 (6.0; 25.0)
0.960
Difference (final-baseline)
−49.4 (34.13)
−49.5 (−64.0; −34.0)
<0.001
−60.9 (47.51)
−53.5 (−74.0; −34.0)
<0.001
0.264
LVEF (%)
Baseline
78.9 (8.50)
80.0 (78.0; 83.0)
70.1 (8.90)
70.0 (68.0; 75.0)
<0.001
Final
73.8 (9.94)
77.0 (70.0; 80.0)
63.0 (7.15)
65.0 (60.0; 70.0)
<0.001
Difference (final-baseline)
−5.1 (9.29)
−3.5 (−5.0; 0.0)
<0.001
−7.0 (8.93)
−6.5 (−10.0; 0.0)
0.001
0.312
LV Dd (mm)
Baseline
41.8 (4.91)
42.0 (40.0; 44.0)
47.3 (5.66)
47.5 (44.0; 53.0)
<0.001
Final
47.0 (5.05)
48.0 (46.0; 49.0)
47.6 (5.49)
47.0 (44.0; 50.0)
0.874
Difference (final-baseline)
5.2 (5.91)
4.0 (2.0; 6.0)
<0.001
0.2 (5.57)
0.0 (−2.0; 5.0)
0.949
0.004
IVS (mm)
Baseline
21.7 (3.96)
20.0 (20.0; 22.0)
23.4 (5.81)
22.0 (20.0; 26.0)
0.207
Final
14.2 (5.63)
13.0 (12.0; 15.0)
20.3 (7.21)
19.0 (17.0; 20.0)
<0.001
Difference (final-baseline)
−7.5 (6.19)
−7.8 (−9.5; −6.0)
0.001
−3.4 (4.01)
−3.0 (−5.0; −2.0)
0.001
<0.001
value: statistical significance of the parameter change in each group. value: statistical significance of the difference in parameter change between both groups.
