Synthesis and Cytotoxicity of Chalcones and 5-Deoxyflavonoids

Table 1

IC₅₀ value (μg/mL) of chalcones and deoxyflavonoids on the cancer cell lines.

Compound	MDA-MB-231	U251	BGC-823	B16
HCPT^a	1.18
Vincristin^b		0.81
Taxol^c			0.002	0.109
2	4.97	2.37	3.42	>10
4	>10	>10	3.87	2.88
5	>10	6.53	3.55	2.66
6	6.17	3.37	3.99	>10
10	4.21	8.33	3.92	>10
15	8.68	4.95	3.71	>10
19	5.49	9.71	4.33	4.77

a,b,cUsed for positive control.