New Urea and Thiourea Derivatives of Piperazine Doped with Febuxostat: Synthesis and Evaluation of Anti-TMV and Antimicrobial Activities

Table 2

The inhibitory activity of the titled urea and thiourea derivatives 8(a–j) on TMV.

Compound^a	Inactivation rate (%) ± SD	Protective effect (%) ± SD	Curative effect (%) ± SD
4	57.54±0.18	39.82±0.97	36.02±0.72
8a	74.41±0.56	41.24±0.76	52.73±1.43
8b	72.55±0.74	40.57±1.28	49.75±0.76
8c	78.43±1.01	52.31±0.84	51.28±0.69
8d	85.72±0.33	58.72±1.18	57.34±0.82
8e	65.28±0.97	39.86±0.49	49.28±0.86
8f	85.93±0.54	58.29±0.76	56.31±0.97
8g	64.56±1.27	45.53±0.86	48.29±1.08
8h	81.33±0.79	58.88±0.78	56.03±1.10
8i	72.74±0.48	50.73±1.25	42.49±0.92
8j	63.26±0.98	47.96±0.44	46.23±0.75
Stand	88.45±0.68	59.62±0.74	57.27±0.54

aThe title compounds tested at 500 µg/L.
Stand: Ningnanmycin, SD: standard deviation.