A Comparative Genomic Study in Schizophrenic and in Bipolar Disorder Patients, Based on Microarray Expression Profiling Meta-Analysis

Table 4

Number of DE genes and probesets, occurring from comparison of SZ or BD gene expression profile and control expression profile. In case of SZ vs control samples genes are characterized as overexpressed when they present positive FC >|0.37| in log₂ scale and in case of BD vs control when they present FC >|0.26| in log₂ scale. Genes are characterized as downregulated when they present the negative FCs respectively. Out of 45000 probesets and 33000 genes of the Affymetrix HG-U133A GeneChips, we derived a much smaller number of probesets and genes.

Disease versus control	Overexpressed genes	Downregulated genes	Total DE genes	Total probesets
SZ versus control	113	103	216	227
BD versus control	69	136	205	210