A Comparative Genomic Study in Schizophrenic and in Bipolar Disorder Patients, Based on Microarray Expression Profiling Meta-Analysis
Table 6
Common DE genes in SZ and BD patients as compared to control samples derived from the fourth study. Top twenty genes (BD) are shown.
Gene symbol
FC (log2) SZ versus control
FC (log2) BD versus control
Gene title
DERL1
−0.9218
−0.59278
Der1-like domain family, member 1
DDX27
−0.58735
−0.55081
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
NELL1
−0.48395
−0.49181
NEL-like 1 (chicken)
WDR41
−0.561422
−0.47103
WD repeat domain 41
SST
−0.56168
−0.47692
Somatostatin
ZYX
−0.55832
−0.4319
Zyxin
SSR1
−0.79829
−0.41544
Signal sequence receptor, alpha fibronectin
FSD1
−0.4133
−0.39578
Type III and SPRY domain containing 1
TRIM27
−0.51857
−0.39195
Tripartite motif-containing
TESC
−0.546183
−0.364501
27 Tescalcin
HES1
0.383441
0.32929
Hairy and enhancer of split 1
MT1H
0.477326
0.329479
(Drosophila) metallothionein 1H
GJA1
0.694821
0.332313
Gap junction protein, alpha 1, 43 kDa
TRIL
0.405464
0.343382
TLR4 interactor with leucine-rich repeats
MT1X
0.60052
0.35402
Metallothionein 1X
AGXT2L1
0.816962
0.375859
Alanine-glyoxylate aminotransferase 2-like 1
GREB1
0.623598
0.418634
Growth regulation by estrogen in breast cancer 1
EMX2
0.975302
0.545582
Empty spiracles homeobox
GPC5
0.772653
0.591493
2 glypican 5
ALDH1L1
1.0583
0.599394
Aldehyde dehydrogenase 1 family, member L1
Downregulation of genes in each disease state is represented with negative FC values (fold decrease) and upregulation with positive FC values. Most statistically significant genes, common in SZ and BD, are differentiated in similar way.
