A Comparative Genomic Study in Schizophrenic and in Bipolar Disorder Patients, Based on Microarray Expression Profiling Meta-Analysis
Table 8
Genes present in DE gene lists from all studies including comparison of gene expression between SZ samples with control samples.
Gene symbol
FC SZ versus control
FC SZ versus control
FC SZ versus control
Gene title
(Study 1)
(Study 3)
(Study 4)
SRGN
0.777085
0.42152
—
Serglycin
PRPF4B
0.563723
—
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
MT1X
0.754667
—
Metallothionein 1X
GYG2
0.754525
—
0.686934
Glycogenin 2
NR4A2
−0.90769
—
−0.550066
Nuclear receptor subfamily 4, group A, member 2
NPY
−0.568144
−0.406243
Neuropeptide Y
SST
−0.83089
—
−0.561683
Somatostatin
PALLD
—
0.509794
0.401231
Paladin, cytoskeletal
Associated protein
AQP4
—
0.449303
0.714565
Aquaporin 4
ARPC1B
—
0.392173
−0.597327
Actin-related protein 2/3 complex, subunit 1B, 41 kDa
PVALB
—
−0.403296
−0.432033
Parvalbumin
HSD11B1
—
−0.413042
−0.538573
Hydroxysteroid(11-beta)dehydrogenase1
PHLDA2
—
−0.452704
−0.455578
Pleckstrin homology-like domain, family A
Downregulation of genes in each disease state is represented with negative FC values (fold decrease) and upregulation with positive FC values. Most statistical significant genes, common in SZ studies are differentiated in similar way.