Table 1: The bioinformatics resources related to alternative splicing (yrs 2001–2013)*.

AsMamDB [104]An alternative splice database of mammals (website is unavailable)
PALS db [105]Putative alternative splicing database
ASAP [106]Alternative splicing annotation project (http://www.bioinformatics.ucla.edu/ASAP/)
EASED [107]Extended alternatively spliced EST database
AVATAR [108]Database for EST and mRNA
MAASE [109]Alternative splicing database designed for splicing microarray (http://maase.genomics.purdue.edu/)
PolyA_DB [110]Database for mRNA polyadenylation in mammalian
AltTrans [111]Annotation for both alternative splicing and alternative polyadenylation
GRSDB [112]Database of quadruplex forming G-rich sequences in alternative splicing sequences (http://bioinformatics.ramapo.edu/grsdb/)
HOLLYWOOD [113]A comparative relational database of alternative splicing (http://hollywood.mit.edu/)
ASD [114]A bioinformatics resource on alternative splicing
Splicy [115]Prediction of alternative splicing from Affymetrix data
ASTALAVISTA [116]Analysis of alternative splicing for custom datasets (http://genome.imim.es/astalavista/)
BIPASS [117]Bioinformatics pipeline alternative splicing services
ECgene [118]Alternative splicing database update (http://genome.ewha.ac.kr/ECgene/)
EuSplice [119]A resource for splice signals and alternative splicing in eukaryotic genes (http://www.genome.com/products-1/integrated-genomics-resources/eusplice)
SpliceCenter [120]A server for analysis of alternative splicing on RT-PCR, RNAi, microarray, and peptide-based studies (http://discover.nci.nih.gov/splicecenter/)
ASPicDB [121]Database for alternative splicing analysis (http://www.caspur.it/ASPicDB/)
The alternative splicing mutation database [122]A hub for analyzing alternative splicing from mutational evidence
ProSAS [123]Database for analyzing alternative splicing in the context of protein structures (http://www.bio.ifi.lmu.de/ProSAS/)
Splice-mediated Variants of Proteins (SpliVaP) [124]Signatures for protein isoforms due to alternative splicing (http://www.bioinformatica.crs4.org/tools/dbs/splivap/)
AspAlt [125]A interdatabase for comparative analysis of alternative transcription and splicing (http://www.genome.com/products-1/integrated-genomics-resources/products-integrated-genomics-resources-igr-aspalt)
ASTD [126]Alternative splicing and transcript diversity database
TassDB2 [127]A comprehensive database of subtle alternative splicing (http://www.tassdb.info/)
H-DBAS [128]Human-transcriptome database for alternative splicing (http://h-invitational.jp/h-dbas/)
SPLOOCE [129]Analysis server of human splicing variants (http://www.bioinformatics-brazil.org/splooce/)
APPRIS [130]Annotation of human alternative splice isoforms (http://appris.bioinfo.cnio.es/)
SpliceAid 2 [131]Database of human splicing factors expression data and RNA target motifs (http://www.introni.it/spliceaid.html)
TFClass [132]Classification of human transcription factors (http://tfclass.bioinf.med.uni-goettingen.de/)

The websites for some resources without function currently are not provided.