Research Article

Alum Catalyzed Simple, Efficient, and Green Synthesis of 2-[3-Amino-5-methyl-5-(pyridin-3-yl)-1,5-dihydro-4H-1,2,4-triazol-4-yl]propanoic Acid Derivatives in Aqueous Media

Table 2

Effect of temperature on the formation of 5a in the presence of alum as catalyst.

EntryTemperature (°C)Time (hrs)Yield (%)

1Room temp.25Nil
2501840
3601556
4701066
580690
6100690