Research Article

Evaluation of Combination Effects of Ethanolic Extract of Ziziphus mucronata Willd. subsp. mucronata Willd. and Antibiotics against Clinically Important Bacteria

Table 2

Susceptibility of the bacterial isolates to Ziziphus mucronata extract and the antibiotic.

Minimum Inhibitory concentrations of extracts and the different antibiotics used in combination
ZMEChloramphenicolAmoxicillinTetracyclineCiprofloxacinNalidixic acidKanamycin
(mg/mL) (µg/mL)

E. coli ATCC 87390.15615.63 (I)15.63 (S)0.977 (S)0.0048 (S)3.906 (S)31.25 (I)
B. cereus ATCC 107020.1563.91 (S)7.813 (S)0.0305 (S)0.0781 (S)15.63 (I)125 (R)
B. subtilis KZN0.3133.91 (S)62.5 (R)0.977 (S)0.0195 (S)7.813 (S)3.906 (S)
P. aeruginosa ATCC 195820.3133.91 (S)3.906 (S)0.488 (S)0.156 (S)7.813 (S)31.25 (I)
S. marcescens ATCC 99860.6250.98 (S)31.25 (I)1.563 (S)0.0781 (S)1.953 (S)1.953 (S)
A. calcoaceticus anitratus 0.3137.81 (S)250 (R)0.49 (S)0.0195 (S)31.25 (S)15.63 (S)
K. pneumoniae ATCC 100310.1561.95 (S)0.977 (S)0.488 (S)0.039 (S)3.906 (S)15.63 (S)
P. vulgaris ATCC 68300.3137.81 (S)250 (R)7.813 (I)0.0195 (S)1.953 (S)31.25 (I)
E. faecalis ATCC 292120.3131.95 (S)3.906 (S)3.906 (S)0.313 (S)31.25 (I)125.00 (R)
S. aureus OK2a0.1567.81 (S)125 (R)0.977 (S)0.0781 (S)31.25 (I)7.813 (S)
S. aureus OK2b0.3137.81 (S)7.813 (S)0.197 (S)0.0195 (S)62.50 (R)31.25 (I)
S. flexneri KZN0.3137.813 (S)250 (R)0.197 (S)0.039 (S)250 (R)15.625 (S)