18F-Fluorothymidine-Pet Imaging of Glioblastoma Multiforme: Effects of Radiation Therapy on Radiotracer Uptake and Molecular Biomarker Patterns
Figure 2
Orthotopic brain tumors are readily imaged by FLT-PET. (a) Visual comparison of Bioluminescence Imaging (BLI) surface radiance (photons/sec/cm2/steradian) in orthotopic intracranial tumors with BLI (photons/second) values of () and (). (b) Identification of an exponential growth pattern in intracranial tumors based on measurements (). (c) Comparison of %ID of intracranial 18F-FLT %ID at 1 and 7 weeks after injection. (d) Visual comparison of 18F-FLT uptake in intracranial tumors based on values of and (weeks 1 and 7, respectively). Tumor visualized at 7 weeks (yellow arrows).
